Hereditary polycystic kidney syndrome

Update Date: 2021-04-12 Source: Network

summary

I have no spirit these days, I can't work hard, and I don't have a good appetite. I eat less, and I feel sick when I see things. The situation is very serious, so I went to the hospital for examination. It turned out that it was hereditary polycystic kidney. Today, let me learn about hereditary polycystic kidney disease.

Hereditary polycystic kidney syndrome

Symptom 1: renal pain is often low back pressure or dull pain, but also severe pain, sometimes abdominal pain. Pain can be aggravated by physical activity, long walking time, sedentary and so on, which can be alleviated after lying in bed. Renal hemorrhage, stone movement or infection are also the causes of sudden severe pain.

Symptom 2: hematuria about half of the patients showed microscopic hematuria, with paroxysmal gross hematuria, which was caused by the rupture of blood vessels in the cyst wall. When bleeding is frequent, the blood clot may pass through the ureter and cause colic. Hematuria is often accompanied by white blood cell urine and proteinuria. The amount of proteinuria is less than 1.0 g / day. Pyuria, hematuria, lumbago and fever were obvious in renal infection.

Symptom 3: hypertension is a common manifestation of polycystic kidney. Before the increase of serum creatinine, about half of the patients have hypertension, which is related to the compression of surrounding tissues by cysts and the activation of renin angiotensin aldosterone system. In the past 10 years, Graham PC, Torre V and Chapman AB all confirmed that renin granules increased in normal renal tissue, interstitial and epithelial cells of cyst, and renin secretion increased. These are closely related to the growth of cysts and the occurrence of hypertension. In other words, the cyst growth in patients with hypertension is faster, which can directly affect the prognosis.

matters needing attention

At present, there is no way to prevent the development of polycystic kidney disease. Early detection, prevention of the occurrence and development of complications, timely and correct treatment of complications is very important.