What medicine does the Parkinson that drug causes take

summary

There are many reasons for Parkinson's disease. My uncle is old and in poor health. He suffers from rheumatism. Later, he suffered from Parkinson's disease probably because of improper medication. In order to treat Parkinson's disease, all kinds of drugs have been adjusted. Let's take a look at the drug-induced Parkinson's disease.

What medicine does the Parkinson that drug causes take

Drug 1: anticholinergic drugs: it can inhibit the effect of acetylcholine and correct the imbalance between acetylcholine and dopamine. It is suitable for patients with early mild disease, and has certain curative effect on tremor and muscle stiffness. The commonly used drug is antam, 2-4mg orally, three times a day. Side effects include dry mouth, eye * ing, no sweat, red face, nausea, insomnia, constipation, retention of urine, hallucinations and delusions. After stopping and reducing the dose, it disappeared. Glaucoma or prostatic hypertrophy is forbidden. In the elderly, it can cause mental retardation. If the patient's age is more than 60 years old, now generally do not use this drug.

Drug 2: amantadine: can promote the release of dopamine, and has the effect of mild activation of dopamine receptor. The usual dosage is 100 m, three times a day. It has good effect on mild disease and little side effect.

Drug 3: monoamine oxidase-B inhibitor: dopamine is oxidized and degraded by MAO-B in the brain, and a large number of oxygen free radicals are produced during its metabolism to damage neurons. In addition, MPTP is oxidized to toxic MPP + through mao-b. therefore, inhibiting the activity of MAO-B can not only prolong the residence time of dopamine in the brain, enhance the curative effect, reduce the dosage of levodopa and its side effects, but also indirectly protect neurons. Commonly used drugs are midopipide (selegiline) and strychnine.

matters needing attention

Middle aged and old people should strengthen physical exercise, especially aerobic exercise, such as walking, fast walking, jogging, Taijiquan, health exercises, etc., in order to delay brain aging. Just suffering from Parkinson's disease, we should pay attention to appropriate, usually more exercise, is conducive to the improvement of the condition.