What disease is minimal disease denatural kidney disease?

summary

Minimal change nephropathy is a group of clinical simple nephrotic syndrome, as the performance of the disease. Under the light microscope, the glomerulus is basically normal, there may be mild mesangial hyperplasia, proximal renal tubular epithelial cells can see steatosis, so it is also known as lipoid nephropathy. Under electron microscope, the glomerulus showed diffuse foot process fusion, and there was no electron dense substance deposition in glomerulus. Immunofluorescence was negative. Minimal change nephropathy accounts for 10% of adult primary nephrotic syndrome. Boys are more likely to occur in children under the age of eight than girls, which is the most common type of nephrotic syndrome in children, accounting for about 80%.

What disease is minimal disease denatural kidney disease?

Clinical manifestations, general manifestations, the disease often no obvious inducement, but also have upper respiratory tract infection and other precursor performance. Obvious edema began in the face, gradually spread to the whole body, and changed with body position. Large amount of proteinuria, selective proteinuria, mainly albuminuria.

Hypoalbuminemia. Hypertension and Scrophularia hand roll, microscopic hematuria only occurred in about 20% of patients, edema is obvious, often accompanied by pre renal azotemia. Small lesions in children, the onset is relatively fast, often occurs after infection or allergy. Nephrotic syndrome is simple, without hematuria, hypertension or renal involvement.

Nephrotic syndrome, glomerulus is normal, mild mesangial hyperplasia, proximal tubular epithelial cells can be seen steatosis. During the period of massive proteinuria, we should rest in bed, but we should keep moderate bed and bedside activities to prevent deep venous thrombosis. Those with obvious edema should be given low salt diet.

matters needing attention

Diuretic detumescence in general, in the application of glucocorticoid treatment for a week, urine volume will increase rapidly, edema can be significantly improved, poor response to hormone treatment, edema can not subside, can be appropriate use of diuretics, if not obvious, can improve pulse injection.