Non metastatic systemic symptoms of lung cancer?

summary

Lung cancer is one of the most malignant tumors that incidence rate and mortality rate increase fastest and is the most dangerous to the health and life of the population. Incidence rate and incidence rate of lung cancer have been significantly increased in recent 50 years. Lung cancer incidence and mortality rate is the first place in all cancers, and the incidence rate of female is second, and the mortality rate is second. The metastasis of different organs can occur in the late stage of lung cancer, which can cause corresponding symptoms, often bring great pain to patients, and even threaten their lives. What about the non metastatic systemic symptoms of lung cancer?

Non metastatic systemic symptoms of lung cancer?

Why is lung cancer prone to brain metastasis? This is because there are a large number of anastomotic branches between the cerebral vessels and the vertebral artery and the venous artery plexus, which supply the brain, so that the lung cancer cells can directly pass through the heart and carotid artery to the brain without the filtration of the pulmonary capillaries and have blood metastasis. According to the analysis of clinical data, patients with one of the following conditions should be highly alert to the beginning or already brain metastasis of lung cancer.

About 50% of lung cancer patients will eventually have multiple bone metastases. In the early stage of bone metastasis, there are no symptoms. Bone isotope scanning can find the diseased bones. The symptoms of bone metastasis are related to the location and quantity of tumor metastasis. For example, chest pain caused by rib metastasis of lung cancer is mostly manifested as pain with definite tenderness points and limited chest wall. Spinal cord metastases cause pain in the middle of the back or the affected area, while bone metastases in the limbs or trunk cause localized pain in this area. Bone metastasis is not the direct cause threatening the life of lung cancer patients, but if the tumor is transferred to the body bearing bone, such as cervical spine, thoracic spine, lumbar spine and other parts, it can cause serious consequences of paralysis. Therefore, the patients with bone metastasis of lung cancer should be treated in time.

Bone is the most common metastasis site of lung cancer, especially small cell lung cancer (SCLC) and poorly differentiated non-small cell lung cancer (NSCLC). Most of them occurred in the axial bone, mainly in the spine, hypochondriac bone and pelvic bone, and rarely in the limbs. There are no clinical symptoms in the early stage of bone metastasis, but pain in the late stage, mainly manifested as local pain of affected bones and joint dysfunction, while the respiratory symptoms are mild or lack, which is easy to be misdiagnosed clinically. It often takes more than one year from bone metastasis to clinical pain. Therefore, patients with lung cancer should not refuse clinical examination because of no pain symptoms, and exclude bone metastasis symptoms. Carcinomatous bone pain is characterized by fixed position, gradual aggravation of pain, and obvious at night; Thoracic vertebrae metastasis can produce banded pain; Lumbar metastasis often occurs along the lateral side of the lower extremities to the lateral side of the foot radiation pain, with cough, defecation and other activities aggravated. Sciatica similar to hyperosteogeny or intervertebral disc prolapse should be paid attention to.

matters needing attention

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