What is the cause of high creatinine

summary

High creatinine is a serious threat to our health. At this time, we must find out the cause of high creatinine in time, so as to suit the remedy to the case. Now I'll tell you what the cause of high creatinine is.

What is the cause of high creatinine

First, high creatinine may be caused by strenuous physical activity, gigantism and acromegaly. Sometimes the content of creatinine in blood and urine may also increase.

Second, high creatinine is common in consumptive diseases, nephritis, dermatomyositis and tetanus, typhoid and typhus. Low creatinine is common in muscle atrophy, leukemia and renal insufficiency.

Third, the high serum creatinine is due to the renal invasion of various causes. First, the damaged inherent cells of the kidney undergo phenotypic transformation, forming pathological changes, stimulating the fibroblasts in the kidney to transform into myofibroblasts. At the same time, it also invades and stimulates the inherent normal renal tissues, resulting in the same pathological changes, thus forming the kidney from point to surface, from local to the whole, expanding During the spreading process of large excitation, it entered the organic damage stage (i.e. renal function damage stage). At this time, due to the continuous damage of the kidney, the function of excreting waste is reduced, resulting in the accumulation of creatinine and other toxins in the body, resulting in the increase of blood creatinine and urea nitrogen, the decrease of urine creatinine, and the decrease of bilateral renal filtration rate.

matters needing attention

People with high serum creatinine must pay attention to it and go to the hospital in time, so as to find and treat it early, so as not to miss the best opportunity for treatment.