Why is glomerulonephritis edematous?

summary

* edema is a change of skin, mainly due to a large amount of fluid retention in the tissue gap, causing swelling of the skin or local skin, decreasing elasticity and weakening the tension. So the key is * a large amount of fluid retention. * the basic pathophysiological changes of renal edema are mainly water and sodium retention. So the following specific introduction of glomerulonephritis why edema? I hope this problem can help some people.

Why is glomerulonephritis edematous?

First: nephrotic edema: a large amount of proteinuria leads to hypoproteinemia, the osmotic pressure of blood colloid decreases, and water flows from blood vessels to interstitial tissue, resulting in edema. At this time, the interstitial protein content is low. Due to the influence of gravity, it first appears in the drooping part, mainly in the lower limbs. When the intravascular load increases, some substances will exude through the vascular wall, just like the transmembrane transport of cells, exuding small molecular substances. When kidney disease occurs, a large amount of albumin is lost with the urine, and there is a lack of albumin in the blood vessels. The osmotic pressure of plasma colloid is reduced, and the liquid infiltrates into the tissue space from the blood vessels, resulting in edema. Because of the difficulty of venous return, it is often swollen from the lower limbs. 　　

Second: nephritis * edema: glomerulonephritis is mainly in glomeruli, glomerular filtration rate is decreased, and renal tubular reabsorption function is relatively normal, which leads to ball tube imbalance, and ball tube imbalance is the main reason for water and sodium retention. There is no obvious hypoproteinemia in nephritis, and the content of interstitial protein is high. Therefore, this kind of edema begins in the relatively loose eyelids and face. With the development of the disease, edema will quickly spread to the whole body.

Third: we can simply think of human beings as a pocket. Drinking water is pouring water into the pocket at ordinary times, and urinating is pouring water out of the pocket. The two behaviors of drinking water and urinating maintain the water balance of our pocket. If this pocket has water only, do not have water, so pocket can be propped up, this is nephritis sex oedema produces mechanism. This edema is caused by excessive renal drainage and excessive water retention in the body, resulting in an absolute increase in the volume of blood vessels, causing the blood in the vessels to exude into the extravascular * tissue gap.

matters needing attention

Which of our human skin tissue has the lowest pressure? Thin skin (less muscle) places low pressure! And the face just conforms to these two, so this kind of edema swells the face first. However, when it is very serious, edema of other parts will also appear.