How to treat Helicobacter pylori
summary
Many people do not understand the disease of Helicobacter pylori, must be treated in time, Helicobacter pylori great harm, and easy to relapse. So how to eradicate Helicobacter pylori? What are the ways to eradicate Helicobacter pylori?
How to treat Helicobacter pylori
First: triple therapy for Helicobacter pylori. Currently, triple therapy is the most commonly used treatment for Helicobacter pylori. Brief introduction to triple therapy: Gastric triple therapy refers to colloidal bismuth or proton pump inhibitor (PPI) + two kinds of antibiotics. Generally speaking, the duration of triple therapy is one to two weeks. In addition, gastric mucosal protective agents, gastric emptying drugs and anticholinergic drugs can be used according to the condition. Advantages of triple therapy: compared with single antibiotic therapy and double therapy, triple therapy has the advantage of high eradication rate. In the past few years, when the drug resistance of Helicobacter pylori was not as common as it is now, the eradication rate of triple therapy could reach 85% - 95%. The problems of triple therapy: the first is the problem of side effects. Almost all commonly used antibiotics have certain side effects. For example, metronidazole, the two most commonly used antibiotics in Sanlian, can cause nausea and tongue burr; amoxicillin and erythromycin can cause diarrhea, nausea, glossitis, allergic urticaria, rash and drug fever. Then, in recent years, the main problem for clinicians is the increase of drug resistance of Helicobacter pylori. Recently, the data released by the sixth clinical diagnosis and treatment forum of Helicobacter pylori showed that due to the improvement of drug resistance, the traditional triple eradication rate of Helicobacter pylori is declining year by year, and the triple eradication rate in some areas has dropped to about 65%.
Second: Helicobacter pylori quadruple therapy quadruple therapy brief introduction: quadruple therapy, refers to colloidal bismuth agent + three kinds of antibiotics. The commonly used drug combinations and dosage are as follows: 1. Potassium bismuth citrate 240mg + amoxicillin 750mg + metronidazole 400mg + omeprazole 20mg 2. Potassium bismuth citrate 240mg + erythromycin 500mg + metronidazole 400mg + omeprazole 20mg 3. Potassium bismuth citrate 240mg + tetracycline 500mg + metronidazole 400mg + omeprazole 20mg 7-14 days as a course of treatment, Continue to take bismuth potassium citrate alone for 6 weeks. The dosage and usage are the same as before. Pay attention to skin test for amoxicillin (amoxicillin is a penicillin spectrum antibiotic) Advantages of quadruple therapy: the remission rate and eradication rate of quadruple therapy in the treatment of Helicobacter pylori infection are higher than triple therapy, in which the remission rate is more than ten percentage points and the eradication rate is several percentage points higher. The drug resistance rate of quadruple therapy is slightly lower than triple therapy, which is the most commonly used first-line treatment for Helicobacter pylori and the second-line treatment after triple therapy failure. Problems of quadruple therapy: due to the addition of an antibiotic, the remission rate and eradication rate of quadruple therapy are higher than triple therapy, and the incidence of side effects is also higher than triple therapy by 5 percentage points, about 30%. Although the drug resistance rate is lower than triple, it is also higher and higher. So the eradication rate of Helicobacter pylori in quadruple therapy is also decreasing year by year. The latest data show that the eradication rate of quadruple therapy has dropped to about 70%.
Third: Helicobacter pylori probiotics therapy with the triple and quadruple eradication rate of Helicobacter pylori decreased year by year, the sixth national clinical Forum on Helicobacter pylori infection and digestive diseases, as well as the round table meeting on the new path of Helicobacter pylori treatment, Helicobacter pylori probiotics therapy has been widely concerned and recognized. Du Yiqi, Hu Fulian and other experts made a detailed introduction to the probiotic therapy of Helicobacter pylori: brief introduction to probiotic therapy: probiotic therapy refers to the method of adding probiotic preparation on the basis of traditional triple and quadruple, or directly using weiyueke probiotic preparation to eradicate Helicobacter pylori. Advantages of probiotic therapy: the current clinical studies at home and abroad show that probiotic therapy can increase the eradication rate of triple and quadruple by 10-20%, and reduce the adverse reactions of triple and quadruple by more than 20%. Probiotics therapy: at present, the main problem is whether probiotics are combined with triple or quadruple or used alone, which is still to be verified.
matters needing attention
1., to change the way of eating, serving of individual dishes or using public chopsticks should be chosen. 2. Drinking boiled water instead of raw water, eating cooked food instead of raw food, and drinking milk after disinfection. 3. Experiments have proved that kissing patients with ulcer disease also has the risk of spreading the disease, so we should be more vigilant. 4. Develop good hygiene habits and wash hands before and after meals. Frequent use of tableware must also be strictly disinfected. 5. Don't put dental appliances and other cleaning supplies in the toilet, but in a ventilated place. And sanitation also needs regular ventilation and sunlight, the bathroom in the shade can use ultraviolet light irradiation, 5-10 minutes. 6. Regularly go to the hospital for Helicobacter pylori examination. 7. Use probiotics regularly to improve gastrointestinal microecology and enhance gastrointestinal immunity.
