How to treat diabetes insipidus?

summary

Diabetes insipidus (DI) is a group of clinical syndromes that the deficiency of arginine vasopressin (AVP), also known as antidiuretic hormone (ADH), is caused by hypothalamus neurohypophysis lesions, or the renal sensitivity to AVP is deficient due to a variety of lesions, leading to the dysfunction of renal tubular reabsorption of water. How to treat diabetes insipidus? Next, I'd like to share my views with you.

How to treat diabetes insipidus?

AVP replacement therapy is mainly used for complete CDI, and partial CDI can also be replaced by AVP when oral medicine is not effective. The substitutes include: vasopressin: the effect only lasts for 3-6h, and it needs to be injected many times a day, which is inconvenient for long-term application.

Chlorfenuron can stimulate the release of AVP from pituitary gland, enhance the water absorption of AVP, and increase the production of camp in renal tubules, but it has no effect on NDI. It can cause serious hypoglycemia and water poisoning, which should be paid attention to.

Hydrochlorothiazide can reduce urine volume by half. The mechanism of action may be due to the increase of excretion of sodium in urine, the lack of sodium in the body, the increase of reabsorption of proximal convoluted tubules, the decrease of primary urine to distal convoluted tubules, and the decrease of urine volume. Long term use can cause potassium deficiency, hyperuricemia, should be appropriate to supplement potassium.

matters needing attention

Lentinus edodes is rich in vitamin B group, iron, potassium and vitamin D. Jujube patients with diuresis at night, easy to get tired during the day, we should pay attention to keep a quiet and comfortable environment, which is conducive to the rest of patients. It has a high nutritional and medicinal value, containing phosphorus, iron, calcium and other trace elements necessary for human body. Tonifying the five zang organs and treating deficiency and damage.