The cause of polycythemia?

summary

Polycythemia is the number of red blood cells, hemoglobin, the total number of blood is obviously more than the normal level. Polycythemia can be divided into relative and absolute polycythemia. Patients with primary polycythemia can also be divided into congenital and acquired polycythemia, the latter is generally true polycythemia. Common symptoms include vomiting, diarrhea, sweating, diabetes, ketoacidosis, etc. The cause of polycythemia? Now let me tell you something.

The cause of polycythemia?

The increase of relativity. The decrease of plasma makes the number of red blood cells increase. Secondary polycythemia and congenital erythropoietin increase are mainly caused by congenital high affinity hemoglobin production and excessive spontaneous production of congenital EPO.

The postnatal increase of cytokine is due to the decrease of oxygen saturation. The degree of erythrocytosis is directly proportional to the degree of hypoxia. The compensatory increase of physiological erythropoietin was found in fetuses, newborns and residents at high altitude. Pathological increased lung disease, such as obstructive emphysema, and abnormal hemoglobin disease with low oxygen carrying capacity.

It is caused by primary polycythemia. Congenital primary polycythemia is caused by the mutation of erythropoietin receptor gene, which increases erythropoiesis. Acquired primary polycythemia, or polycythemia vera, is a bone marrow proliferative tumor with polycythemia. It is believed that it is caused by the mutation of pluripotent hematopoietic stem cells.

matters needing attention

Polycythemia is the number of red blood cells, hemoglobin, the total number of blood is obviously more than the normal level. Polycythemia can be divided into relative and absolute polycythemia. Patients with primary polycythemia can also be divided into congenital and acquired polycythemia, the latter is generally true polycythemia. For secondary polycythemia, the treatment should start from its etiology. For the symptoms of polycythemia, it is mainly to avoid causing acute leukemia.