Symptoms of avian influenza?

summary

Human infection with avian influenza is a human disease caused by avian influenza virus. Avian influenza virus (AIV) belongs to influenza A virus. According to the different pathogenicity of AIV to chickens and turkeys, it can be divided into three levels: high, medium and low / non pathogenicity. Because of the hemagglutinin structure and other characteristics of avian influenza virus, it is generally infected with birds. When the virus gene rearranges in the process of replication, resulting in structural changes and acquiring the ability to infect people, it is possible to cause human infection with avian influenza. Symptoms of avian influenza? Let's talk about it

Symptoms of avian influenza?

In the early stage of onset, the patient presented with influenza like symptoms, including fever, cough, headache, muscle soreness and general discomfort, as well as runny nose, stuffy nose and sore throat. Some patients with severe lung disease or rapid development of disease, chest tightness and dyspnea and other symptoms.

Respiratory symptoms appear earlier, usually within one week after the onset, lasting for a long time. Some patients still have severe cough and expectoration after one month of treatment. Chest tightness, shortness of breath and dyspnea are common symptoms in the early stage of the disease, which often indicates that the lung lesions progress rapidly and will rapidly develop into severe hypoxia and respiratory failure.

Severe patients develop rapidly, most of them have severe pneumonia in 5-7 days, most of them have body temperature above 39 ℃, dyspnea and hemoptysis; It can rapidly progress to acute respiratory distress syndrome, sepsis, septic shock, and some patients may have mediastinal emphysema, pleural effusion, etc. There are a considerable proportion of severe patients with multiple system or organ damage or failure at the same time, such as heart failure caused by myocardial injury. Individual patients also have digestive system symptoms such as gastrointestinal bleeding and stress ulcer, and some severe patients have coma and disturbance of consciousness.

matters needing attention

Symptomatic maintenance mainly includes bed rest, dynamic monitoring of vital signs, physical or drug cooling. Anti infective treatment includes antiviral treatment (such as oseltamivir, zanamivir, and palamivir), but the clinical treatment time should be "early, fast, and accurate". In particular, before the use of antiviral drugs, respiratory tract specimens should be taken, and should be used within 48 hours of the onset of the disease as far as possible. For patients who clinically think that antiviral drugs need to be used, they can also be used more than 48 hours after the onset of the disease.