How is the day shift caused by external factors

summary

I had vitiligo on my hand before, and I didn't care too much because I was busy with my work. Now the white spots have spread, on my arm, and around my neck, there are signs of long white spots. How does the day shift for external causes cause this problem? Do you want to discuss it together? Now let's share how the day shift caused by external factors.

How is the day shift caused by external factors

First: vitiligo is a common acquired localized or generalized skin depigmentation disease. However, the mechanism is still unclear. It can occur in all parts of the body, common in finger back, wrist, forearm, face, neck and around genitalia. The decrease of copper or ceruloplasmin levels in the blood and skin of patients with vitiligo leads to the decrease of tyrosinase activity, which affects the metabolism of melanin.

Second: female vulva can also occur, young women in the majority. Vitiligo can appear in twins and families, indicating that heredity plays an important role in the pathogenesis of vitiligo. Studies have shown that vitiligo has incomplete penetrance and multiple pathogenic loci. Vitiligo can be combined with autoimmune diseases, such as thyroid disease, diabetes, chronic adrenal insufficiency, pernicious anemia, rheumatoid arthritis, malignant melanoma and so on.

Third: mental factors are closely related to the onset of vitiligo. Most patients have mental trauma, excessive tension, depression or depression at the onset or skin lesion development stage. The degeneration of nerve endings in leukoplakia also supports the neurochemical theory. Antibodies and T lymphocytes can be produced in patients with vitiligo, indicating that the immune response may lead to the destruction of melanocytes.

matters needing attention

In life and work, we should timely adjust our mentality, restrain abnormal emotional reactions, and improve our adaptability to the environment. How to resolve the pressure in time, maintain physical and mental health, reduce the occurrence of diseases, we should establish a correct outlook on life, with a peaceful attitude to cope with changes in the environment.