What are the manifestations of nephrotic syndrome

summary

A friend of mine has been suffering from kidney disease for many years. He has been in pain all the time. We all told him to insist on treatment, sooner or later will recover. Kidney disease has many complications, so be careful when you get kidney disease. Today, I'd like to talk about the manifestation of nephrotic syndrome.

What are the manifestations of nephrotic syndrome

First, large amount of proteinuria is a sign of nephrotic syndrome. The main component is albumin, and it also contains other plasma protein components. The change of glomerular basement membrane permeability is the basic cause of proteinuria. The change of charge barrier and mechanical barrier (glomerular capillary pore barrier), the reabsorption and catabolism ability of renal tubular epithelial cells also affect the formation of proteinuria.

Second: hypoproteinemia is the second essential feature of nephrotic syndrome. Serum albumin is lower than 30g / L. the synthesis of white protein by liver is increased in nephrotic syndrome. When sufficient protein and calorie are given in the diet, the synthesis of albumin by liver is about 22.6g per day, which is significantly higher than that of normal people's 15.6g per day. When the compensatory effect of synthetic albumin by liver is insufficient to make up for urinary protein Hypoproteinemia occurs only when the amount of urine protein is lost. Hypoproteinemia and urinary protein excretion are not completely consistent.

Third: Hyperlipidemia: the total cholesterol and triglyceride of the disease increased significantly, the levels of low density lipoprotein (LDH) and very low density lipoprotein (vldh) increased, hyperlipidemia was related to hypoalbuminemia, LDL / hldl increased only when serum albumin was lower than 10 ~ 20g / L, HDL was normal or decreased, LDL / HDL ratio increased, which increased the risk of arteriosclerotic complications Hyperlipidemia is associated with thrombosis and progressive glomerulosclerosis.

matters needing attention

Although it's hard to get kidney disease, taking medicine can relieve it. As long as patients adhere to treatment, and then listen to the doctor's arrangement, appropriate exercise, appropriate to eat some food conducive to recovery.