Symptoms of nitrobenzene poisoning?

summary

Nitrobenzene is a colorless oily liquid with bitter almond flavor, which is insoluble in water and has higher density than water. Nitrobenzene is toxic, nitrobenzene can cause poisoning when it comes into contact with skin or its vapor is absorbed by human body. Nitrobenzene is easily soluble in alcohol and ether. The safety reagent for washing nitrobenzene off the skin is alcohol. Generally, ether is not used, because ether is easy to anesthetize people. Symptoms of nitrobenzene poisoning? Let's talk about it

Symptoms of nitrobenzene poisoning?

Methemoglobinemia caused by acute toxicant is the main pathological basis. When methemoglobin reaches 10-15% of the total hemoglobin, the mucous membrane and skin of the patient begin to appear purple inlay. At first, the lips, nails, cheeks, ear shells and other places are blue brown, and the color change of the tongue is the most obvious, showing obvious lavender

When the level of methemoglobin is more than 30%, neurological symptoms such as heavy head, head distension, dizziness and headache will appear one after another. When the level of methemoglobin reaches 50%, symptoms of hypoxia will occur, such as palpitation, chest tightness, shortness of breath, etc. when the kidney is damaged, symptoms such as oliguria, proteinuria and hematuria will appear. In severe cases, there will be no urine. In the early stage of relieving aniline, patients may have urgency and frequency of urination, The symptoms of bladder irritation were similar in birds,

Due to hemorrhagic chemical inflammation. Chronic poisoning patients often have neurasthenia syndrome, such as headache, dizziness, weakness, insomnia, dreaminess, sometimes with bradycardia or tachycardia, hyperhidrosis, digestive disorders, etc., severe cases can also have peripheral nerve damage, sensory abnormalities, limb numbness, etc

matters needing attention

First aid and treatment of acute poisoning: move the patient to a place with clean air, keep quiet, take off the contaminated clothes immediately, wash the reading materials on the skin with a large amount of 5% acetic acid, then wash with soapy water and slightly warm water, pay special attention to the hands, ancestral nails and other parts, and wash the eyes with a large amount of normal saline, If necessary, carry out artificial respiration. Deal with methemoglobinemia. If mild symptoms appear, only need to rest and send sugar drinks. When mild poisoning, give 50% glucose solution 40-60 ml, if 0.5-1.0 g vitamin intravenous injection. For moderate poisoning, give 1% methylene blue solution 5-10 ml, However, methemoglobin is mostly reduced in about 1 hour. For severe poisoning, 10-20 ml of 1% methylene blue can be used. If purple inlay does not appear again, it can be given after a period of time. For severe hemolytic anemia, in addition to blood transfusion, oral prednisone 30-50 mg per day or oxycortisone 100-200 mg per day can be given intravenously