Late symptoms of multiple system atrophy?

summary

Multiple system atrophy (MSA) is a group of degenerative diseases or syndromes with multiple progressive atrophy of nervous system. Pathologically, it mainly accumulated striatal substantia nigra system (substantia nigra degeneration), olivopontocerebellar system (olivopontocerebellar atrophy) and autonomic nervous system. Late symptoms of multiple system atrophy? Let's talk about it

Late symptoms of multiple system atrophy?

Further progress will appear two or more systems of neurological symptoms. * urinary incontinence, frequent urination, urgency and urine retention, male erectile dysfunction, orthostatic hypotension, dysphagia, pupil size and Horner syndrome, asthma, apnea and dyspnea.

Cerebellar ataxia is a prominent symptom of MSA-C subtype and one of the common symptoms of other MSA subtypes. The clinical manifestations are progressive gait and limb ataxia, starting from the lower limbs, especially the lower limbs, with obvious cerebellar ataxia such as dysarthria and nystagmus. Examination can find cerebellar lesions with severe lower limb involvement. When combined with corticospinal tract and extrapyramidal symptoms, cerebellar signs are often masked.

Sleep disorders include sleep apnea, abnormal sleep structure and REM sleep behavior. Other extrapyramidal symptoms: dystonia, palatal clonus and myoclonus were all visible. Myoclonus sensitive to hand and face stimulation was the characteristic manifestation of MSA.

matters needing attention

Guide patients to high sodium, high potassium diet, daily drinking water 2 ~ 2.5L, record the intake and output, adjust according to the actual situation, in order to maintain a stable blood pressure and circulating blood volume. The principle of diet is to eat less and eat more, avoid eating too much. The increase of gastrointestinal blood flow leads to insufficient blood supply to the brain, and aggravates the symptoms of dizziness and dizziness.