Symptoms of chromosome 16 abnormalities

summary

Chromosome is congenital, it is impossible to change, and it can not be treated. Chromosomal abnormalities may also lead to fetal malformations, abnormal development or abortion. However, chromosomal abnormalities are not the "patent" of elderly women. If "invasive prenatal diagnosis" is only provided to elderly women, young pregnant women will not be protected. Moreover, most pregnant women are under 35 years old. Tell us about the symptoms of chromosome 16 abnormality

Symptoms of chromosome 16 abnormalities

The study found that during the 15-20 weeks of pregnancy, some hormonal quantitation in the blood of pregnant women is related to Down's syndrome. Therefore, "Down's screening in mid pregnancy" came into being. It was widely used in the 1990s. Pregnant women of any age can have blood test in mid pregnancy. If they are at high risk, amniocentesis can be performed. In this way, 70% of Down's syndrome can be detected.

Large scale studies have also found that some hormonal quantities in pregnant women's blood can also be used for Down's screening. Therefore, during the period of 11 to 13 weeks, the combination of pregnant women's age, hormonal quantities in blood and fetal neck skin thickness has become "Down's screening in early pregnancy", which is called "Oscar" in English for short. It has gradually become popular in the late 2000s. The sensitivity of this "skin test" and "blood test" is 90%.

Whether in the second trimester or the first trimester, there is 5% false positive in Down's screening, which means that 5% of pregnancies will be labeled as high risk, but the fetus is actually normal.

matters needing attention

The biggest problem of "false positive" is to cause panic. Before Down's screening, pregnant women can only choose "invasive examination" to make a diagnosis, thus increasing the risk of miscarriage.