Symptoms of olfactory neuroblastoma?

summary

Olfactory neuroblastoma originates from the neuroectoderm of the olfactory nerve. If the disease is serious, surgical treatment should be carried out. It accounts for 3% of nasal tumors. In the past, it was considered as benign or low-grade malignant tumor. Because its exact tissue source is not clear, it has been named as olfactory neuroepithelioma and olfactory neuroblastoma, Sensory neuroblastoma. Now let's share with you about the symptoms of olfactory neuroblastoma? Experience in this area.

Symptoms of olfactory neuroblastoma?

First, most of the primary lesions are located at the top of the nasal cavity. Clinically, most of them have symptoms of epistaxis and nasal obstruction, and a few of them have olfactory impairment or loss. When the lesions invaded the adjacent structures, the corresponding exophthalmos, vision loss, headache and cranial nerve damage may appear. The main symptoms included unilateral nasal obstruction (70%) and epistaxis (46%). The rare manifestations included loss of smell, headache, excessive tears and blurred vision. It is characterized by long-term persistent symptoms caused by slow tumor growth. The average time from the first symptom to the final diagnosis was 6 months.

Second, X-ray features include a "sub bell shaped" mass extending through the cribriform plate. The extent of lesions can be well demonstrated in the contrast of T1 weighted MRI and T2 weighted MRI after gadolinium injection on the basis of T1 weighted MRI. The fine changes of bone erosion (paper template, cribriform plate and ethmoidal fovea) can be well displayed in CT scan, and the spot shape caused by calcification can be seen in X-ray film. Angiographic findings were angioproliferative tumors.

Third: the X-ray features of olfactory neuroblastoma include "dumbbell shaped" mass, the mass extends through the cribriform plate, and the lesion range is well shown in the contrast of MRI T1 weighted image and T2 weighted image. The fine changes of bone erosion (paper template, cribriform plate and ethmoidal fossa) can be well displayed in CT scan, and the spot shape caused by calcification can be seen in X-ray film. Angiographic findings were angioproliferative tumors.

matters needing attention

CLS cell immunotherapy is the first high-tech enterprise of tumor immunotherapy industrialization in China. It is a cell immunotherapy (T cells, NK cells) developed by CLS in cooperation with American scientific research institutions. It also extracts patients' own immune cells for in vitro culture. It uses its own cells to treat its own diseases, and bone will not have side effects such as rejection, More than one thousand tumor patients have received CLS autoimmune cell therapy, which is the most mature, effective and widely used tumor biotherapy technology!