How to treat myasthenia gravis
summary
The entry of winter brings a lot of inconvenience to the patients, and it often blows with strong wind, which brings more chances for the patients to invade the disease under the condition of extremely low temperature and large temperature difference. As a more complex disease, how can myasthenia gravis be treated?
How to treat myasthenia gravis
Treatment 1: adrenocortical hormone. Myasthenia gravis is an autoimmune disease. Suprarenal cortical hormone is a commonly used drug in the treatment of autoimmune diseases. At present, high-dose shock therapy, medium dose shock therapy and low-dose maintenance therapy are generally used in the treatment of myasthenia gravis in China. Studies have confirmed that adrenocortical hormone is an inducer of thymocyte apoptosis It can induce thymocyte apoptosis in vivo and in vitro.
Treatment 2: azathioprine, which is a non-specific immunosuppressant, can inhibit the synthesis of DNA, RNA and protein, thereby inhibiting gene replication and T cell activation, playing a role in the treatment of myasthenia gravis. Indications: the dosage of adrenocortical hormone should be reduced; adverse reactions: neutropenia, abnormal liver function, etc. Studies have shown that long-term use of azathioprine can increase the risk of malignant tumor.
Treatment 3: cyclophosphamide. Cyclophosphamide is a compound composed of nitrogen mustard and phosphoramide group. It is a commonly used alkylating agent immunosuppressant in clinic. It can be used for the treatment of various autoimmune diseases. Generally, the symptoms begin to improve within 2 months, and the dosage is reduced and maintained after 5 years. Indications: it is only used for those who are ineffective or intolerable to other mg drugs; adverse reactions: leukopenia, alopecia, hemorrhagic cystitis, etc.
matters needing attention
I also want to emphasize: once suffering from myasthenia gravis, although it has a great impact on the life and work of patients, therefore, in order to avoid it, we should always do a good job in daily life prevention, away from myasthenia gravis. Patients should have reasonable living habits, go to bed early and get up early, and don't overwork and stay up late.