Early symptoms of Karnofsky's pneumonia?

summary

If you or your child has restlessness, cough, accelerated breathing, cough, cyanosis, three concave sign, nasal fan, diarrhea, insignificant fever, and few rales during auscultation, you should pay attention to that you or your child are likely to have Pneumocystis carinii pneumonia. The course of Pneumocystis carinii pneumonia developed rapidly, and most of them died without treatment. Early symptoms of Karnofsky's pneumonia? I'd like to share my views with you.

Early symptoms of Karnofsky's pneumonia?

Pneumocystis carinii pneumonia, also known as Pneumocystis carinii pneumonia, Pneumocystis pneumonia, is a interstitial plasma cell pneumonia caused by Pneumocystis carinii, which is a conditional pulmonary infectious disease. The disease was seen only in preterm infants before 1950s. Malnutrition infants, with the application of immunosuppressive drugs in recent 10 years, the popularity of chemotherapy, especially the emergence of HIV infection, has increased incidence rate, and has become the most common opportunistic infection and death cause of HIV infection.

The incubation period of Pneumocystis carinii pneumonia was 4-8 weeks. The incubation period of patients is longer, with an average of 6 weeks, even up to 1 year. The course of the disease is relatively slow, progressive, first weight loss, night sweats, lymphadenectasis, general discomfort, and then the above respiratory symptoms, lasting for weeks to months.

All patients died of respiratory failure without treatment. The symptoms of Pneumocystis carinii pneumonia are serious, but the pulmonary signs are few. Most patients have no abnormal auscultation, and some patients can hear scattered moist rales. The symptoms of Pneumocystis carinii pneumonia are similar to those of bacterial pneumonia, viral pneumonia and fungal pneumonia. Generally speaking, the symptoms of Pneumocystis carinii pneumonia are classified into infant type and child type.

matters needing attention

A. Do pathogen treatment. The first choice is trimethoprim plus sulfamethoxazole for 2 weeks, but the side effects are far rare, such as skin allergy and gastrointestinal reactions. Supportive therapy includes the use of human blood gamma globulin, which can enhance immunity; B. Oxygen if necessary. If the disease occurs during the application of adrenocortical hormone, the dosage should be reduced or stopped. In order to prevent cross infection of the disease in high-risk children, respiratory tract isolation is advocated until the end of treatment; C. Symptomatic treatment, bed rest, more water and a small number of times into the soft diet, supplement sufficient vitamins and protein, intravenous infusion, etc. At present, it has been proved that the more effective virus inhibition drugs, such as ribavirin (ribavirin), acyclovir, arabinose adenosine, amantadine, interferon, etc., can be used as appropriate; D. The treatment of Pneumocystis carinii pneumonia may have adverse reactions. The disease was treated by single supportive therapy (such as oxygen inhalation, antibiotics, blood transfusion, good nursing, etc.). After treatment, most of the lesions disappeared in a short period of time, leaving no trace, but some patients left pulmonary fibrosis.