How can albuminuria be on the high side

summary

For urinary protein, I believe we are not unfamiliar, because the urine protein phenomenon of more and more friends, let a lot of people are very worried, afraid of suffering from disease. So, how can albuminuria on the high side

How can albuminuria be on the high side

Urine protein can damage the renal tubulointerstitium. A small amount of small molecular protein filtered by normal glomerulus is reabsorbed by the proximal tubular epithelial cells and decomposed in lysosomes. Under pathological condition, the increase of glomerular permeability makes a large amount of plasma protein leak into the renal tubules, and the excessive reabsorption of albumin by proximal renal tubular epithelial cells leads to the increase of lysosomal activity in the cytoplasm, which can cause cell damage.

Urinary protein has toxic effect on glomerular mesangial cells. After renal failure, a large number of plasma proteins will deposit in glomerular mesangial area. The deposition of these macromolecular substances in glomerular mesangial area can cause mesangial cell damage, mesangial cell proliferation and mesangial matrix formation, leading to glomerulosclerosis.

Proteinuria is a mechanism of human body. Generally speaking, persistent proteinuria often represents the degree of kidney rubbing. The amount of proteinuria reflects the degree of rubbing. Clinical curative effect can be observed based on this. Pathological proteinuria is generally caused by kidney disease. Proteinuria is mainly caused by the serious damage of glomerular filtration barrier

matters needing attention

With the improvement of people's living standards, there are more and more patients with high urinary protein. We should pay more attention to diet. At the same time, we should pay more attention to our daily habits. Such as appropriate exercise is more beneficial to the body.