How is macular before membrane caused?

Update Date: 2021-08-26 Source: Network

summary

The patients without definite reason are called epimacular membrane patients; Secondary epimacular membrane occurs in rhegmatogenous retinal detachment and its reduction surgery (such as photocoagulation, coagulation, electrocoagulation, intraoperative or postoperative bleeding, postoperative uveitis reaction), chorioretinitis, retinal vascular occlusion, diabetic retinopathy, eye trauma, vitreous hemorrhage). How is macular before membrane caused? Let's talk about it

How is macular before membrane caused?

Posterior vitreous detachment: most of the clinical primary epiretinal membrane (80% - 95%) occurs after posterior vitreous detachment, which is in line with the law of senile vitreous changes, so it is more common in the elderly. In the process of posterior vitreous detachment, due to the traction of the vitreous body on the retina, the inner limiting membrane of the retina is broken and the stellate cells on the surface of the retina are stimulated to penetrate

The damaged inner limiting membrane migrated to the inner surface of retina; On the other hand, the loss of vitreous attachment on the retinal surface is conducive to the proliferation of retinal surface cells and migration to the macular area. In addition, after posterior vitreous detachment, the thin layer of posterior vitreous cortex and vitreous cells on the surface of macula promote the migration and retention of retinal surface cells to macula.

Cell migration: the cellular and extracellular components of epimacular membrane were studied by immunohistochemistry and electron microscopy. The main cellular component in the primary epimacular membrane is m ü They can pass through the intact inner limiting membrane. The second is pigment epithelial cells, which may have the ability to cross the nonporous retina or migrate to the inner surface of the retina through the peripheral microholes.

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Recovery period (early recovery period): the ability of eyes was enhanced, and the clinical symptoms disappeared. Metaphase of recovery: osmotic activation repair, produce the key material to repair damaged cells. Later stage of recovery: make the damaged part recover vitality and health gradually;