Symptoms and prevention of lead poisoning?
summary
Lead is a widespread industrial pollutant, which can affect the functions of human nervous system, cardiovascular system, skeletal system, reproductive system and immune system, and cause diseases of gastrointestinal tract, liver, kidney and brain. The main way to prevent lead poisoning is to cut off the pollution source, stay away from the pollution area and improve the dietary structure. The method to treat lead poisoning is to use metal chelating agent to promote the excretion of lead. Symptoms and prevention of lead poisoning? Let's talk about it
Symptoms and prevention of lead poisoning?
Lead poisoning anemia is not only due to the decrease of hemoglobin synthesis, but also due to the shortening of red blood cell life. Lead can inhibit the activity of Na + - K + ATPase in erythrocyte membrane, make K + ions in erythrocyte escape, and cause cell membrane collapse and hemolysis. In addition, lead combines with phosphate on the surface of red blood cells to form insoluble lead phosphate, which increases the mechanical fragility of red blood cells and is also the cause of hemolysis. Hemolysis is obvious in acute lead poisoning, but it is not important in chronic lead poisoning
Lead poisoning anemia is not only due to the decrease of hemoglobin synthesis, but also due to the shortening of red blood cell life. Lead can inhibit the activity of Na + - K + ATPase in erythrocyte membrane, make K + ions in erythrocyte escape, and cause cell membrane collapse and hemolysis. In addition, lead combines with phosphate on the surface of red blood cells to form insoluble lead phosphate, which increases the mechanical fragility of red blood cells and is also the cause of hemolysis. Hemolysis is obvious in acute lead poisoning, but it is not important in chronic lead poisoning
Long term lead exposure can lead to high blood pressure, toxic myocarditis and myocardial damage. Lead can increase oxygen free radicals in the body, produce lipid peroxidation damage, including myocardial cell membrane and myocardial microsomal membrane, and can affect the cation transport enzyme of myocardial microsomal membrane, overload Ca2 + ions in aorta and other vascular cells, accumulate Ca2 + in myocardial cells, cause membrane ion transport disorder, and lead to myocardial cell dysfunction.
matters needing attention
The most effective measure to prevent lead poisoning is to cut off the source of pollution and reduce the pollution of all kinds of garbage to our living space. In order to reduce the harm of lead toxicity, we should first avoid the contact with lead, such as the treatment of automobile exhaust, the promotion of the use of lead-free gasoline, and the development of lead-free pigments and coatings. Do not eat or eat less lead containing foods, such as preserved eggs, puffed foods, tinned drinks, popcorn, etc., as well as foods easily contaminated by lead dust. Do not drink tap water stored in lead containing pipes for a long time. In the morning, drain the water in indoor lead containing pipes overnight before use. Pregnant women should not use cosmetics, hair dyes, to avoid lead through the placenta for maternal fetal operation, resulting in neonatal blood lead.
