Is delayed drug allergy serious?

summary

Drug allergy, also known as drug allergy, is an allergic reaction caused by drugs. It is a special type of adverse drug reactions. It is related to people's specific allergic constitution, only seen in a few people. With the development of medical and health undertakings, the disease has an increasing trend, and its prevention should be highly valued by doctors and patients themselves. What symptom does drug allergy have? Let's talk about it.

Is delayed drug allergy serious?

Urticaria and angioedema type of drug eruption, this kind of drug eruption is more common. The rash is characterized by the occurrence of different sizes of wheal, lasting for a long time. Conscious pruritus can be accompanied by tingling and tenderness. It may be accompanied by local edema around the wind mass. Rash can appear as the only symptom, and also as a symptom of serum sickness like syndrome and anaphylactic shock.

Fixed erythema is the most common drug eruption, accounting for 22% - 44% of drug eruption. The common pathogenic drugs are sulfonamides (long-acting sulfonamides are the first), tetracyclines, antipyretic analgesics and sedatives. Edematous patches are round or oval with clear edges. In severe cases, there are one or more blisters or bullae on the patches. The number of erythema varied from one to several, and the distribution was asymmetric. Can occur in any part, often occurs in the lip and genitalia and other skin mucosa junction, often caused by friction erosion. If relapse, usually still in the original attack, with the previous left pigment spots completely or partially overlap, and often than the previous expansion, increase. Local lesions may be accompanied by pruritus, and patients with extensive lesions may have different degrees of fever. After the erythema subsides, it often leaves purple brown pigment spots, which do not subside for many years, so it has diagnostic value. A small number of edematous erythema without purple, then subsided quickly, and may not leave traces. Individual cases may be accompanied by erythema multiforme like drug eruption, urticaria like drug eruption or measles like erythema.

Severe erythema multiforme drug eruption is a severe bullous erythema multiforme. In addition to skin damage, serious mucosal damage occurs in eyes, mouth and external genitalia, with obvious erosion, exudation and pain. It is often accompanied by chills and high fever. It can also be complicated with bronchitis, pneumonia, pleural effusion and kidney damage. Eye damage can lead to blindness. Children with this type of drug eruption are more common.

matters needing attention

(1) Mild cases: ① oral administration of 1-2 antihistamines. ② Vitamin C was given intravenously. ③ 10% calcium gluconate or 10% sodium thiosulfate were injected intravenously. ④ Topical application of calamine lotion containing camphor or peppermint can relieve itching, heat dissipation and inflammation many times a day, and can be cured in a week or so（ 2) The patients with more severe condition: 1. ② Apply the above medicine. ③ Prednisone oral, generally about 2 weeks can completely recover.