Can congenital syphilis turn negative?

Update Date: 2025-02-03 Source: Network

summary

Congenital syphilis is also known as fetal syphilis. The pathogen infects the fetus through the placenta in the mother, which can cause stillbirth and premature birth. Almost all of the fetuses will be affected when the mother is infected in the early stage without treatment, and 50% of the fetuses will have abortion, premature delivery, stillbirth or death in the neonatal period. Can congenital syphilis turn negative? Let's talk about it

Can congenital syphilis turn negative?

The diagnosis of neonatal congenital syphilis should be treated immediately. Because Treponema pallidum is very sensitive to penicillin, penicillin treatment is the only choice, and penicillin drug toxicity is low, cheap. But to use enough and course of treatment, that is the key to the success of treatment, standardized treatment can be cured.

All infants suspected or diagnosed with congenital syphilis should have cerebrospinal fluid examination before treatment. If cerebrospinal fluid RPR is positive or abnormal (white blood cell count > 5 / rr13 or protein > 500g / L), neurosyphilis should be treated. Penicillin is the most effective drug in the treatment of syphilis. For children without serious complications, the clinical cure rate is nearly 100%. To early, timely and active treatment.

Within 7 days after birth, crystalline penicillin g50000 U / kg was given intravenously every 12 hours, and then every 8 hours for 10 days; Or after birth, procaine penicillin 50000 U / kg, intramuscular injection once a day, a total of 10 days. After neonatal period: Penicillin G 50 000 U / kg was injected intravenously every 4-6 hours for 10-14 days.

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Disinfection and isolation: 95% of congenital syphilis was transmitted through neutral contact, mainly through the damaged skin and mucous membrane during sexual intercourse. Early congenital syphilis is the most infectious, daily life contact such as contact with contaminated clothing, tableware, Bathware, toilet can be infected, but also through blood, kissing, lactation, iatrogenic infection.