How to treat children with Streptococcus pneumoniae pneumonia?

summary

Streptococcus pneumoniae pneumonia refers to the acute lung inflammation caused by Streptococcus pneumoniae. Streptococcus pneumoniae often causes inflammation in lobar or segmental lung, which is primary. It is more common in children over 3 years old, especially in older children. Therefore, the body's defense ability in this age group gradually matures. It can limit the lesion to one lobar or segmental lung without spreading, so it is also called lobar pneumonia. Let's share my experience with you.

How to treat children with Streptococcus pneumoniae pneumonia?

Antibiotic treatment: Penicillin G or amoxicillin (amoxicillin) is the first choice for penicillin sensitive patients; Penicillin G is still the first choice for patients with low degree of resistance to penicillin, but the first or second generation cephalosporins, ceftriaxone or cefotaxime or vancomycin can also be used if the dosage is increased. Vancomycin or ceftriaxone or cefotaxime is the first choice for patients with high penicillin resistance or risk factors.

The commonly used dose of penicillin is 5-100 000 U / (kg · d), or 600-10 million U or more per day, intramuscular injection or intravenous administration in four times. Children with penicillin allergy can be given intravenous injection of erythromycin 100mg / (kg · d), and oral administration can be changed after improvement.

The treatment should last for 1-2 weeks or 3-5 days after complete fever abatement. If the patient's condition is not improved after 2-3 days of penicillin treatment, the occasional penicillin resistant strains should be considered and other antibiotics should be used. Other drugs can be used according to the sensitivity test results of Streptococcus pneumoniae cultured from throat swab. The patients with septic shock, brain edema and brain hernia should be rescued according to the description of septic shock or intracranial hypertension.

matters needing attention

In some countries and regions, the high-risk groups of Streptococcus pneumoniae infection (including children, especially children with sickle cell disease) try to use polyvalent Streptococcus pneumoniae polysaccharide vaccine for prevention, which is considered effective. It is still under study.