How to treat lupus erythematosus?

summary

Lupus erythematosus is one of the autoimmune diseases, which belongs to the scope of connective tissue disease. Lupus erythematosus is divided into discoid lupus erythematosus (DLE), systemic lupus erythematosus (SLE), subacute cutaneous lupus erythematosus, deep lupus erythematosus and other types. The onset of lupus erythematosus is slow and insidious, and its clinical manifestations are diverse and changeable. How to treat lupus erythematosus? Let's talk about it

How to treat lupus erythematosus?

Avoid sunlight, especially for those who are sensitive to sunlight. Go out should pay attention to sunscreen, avoid using photosensitive drugs, such as phenothiazine, hydrochlorothiazide, sulfonamides and griseofulvin. Avoid overwork, acute or active SLE should stay in bed. Avoid pregnancy, should not take contraceptives, renal function damage or multi system damage contraceptive failure, early treatment of abortion.

Systematic treatment: 1. Antimalarial drugs such as hydroxychloroquine were reduced to half dosage when the condition improved. Generally, the total course of treatment is 2-3 years. ② Thalidomide can be used for trial. When the effect appears, the drug is reduced and maintained, and the treatment is continued for 3-5 months. It is effective in most patients, but it is easy to relapse when the drug is stopped. ③ Low dose of hormone can be taken orally in patients with generalized disease.

Individualization is very important. Before treatment, the disease activity of SLE patients must be evaluated, such as antinuclear antibody, anti DNA antibody, hypocompleminemia and organ damage, such as heart, kidney, lung disease, skin and serositis, before treatment. At present, systemic lupus erythematosus activity index (SLEDAI) is commonly used. Based on the clinical manifestations of patients before 10 points of evaluation, it is suggested that when SLEDAI > 12 points, double dose of glucocorticoid or hospitalization should be used.

matters needing attention

1) We should be optimistic, treat the disease correctly, build up the confidence to overcome the disease, regularize our life, pay attention to the combination of work and rest, take proper rest and prevent infection. 2) Remove all kinds of inducements, including all kinds of possible internal medicine, chronic infection focus, etc., avoid irritant external medicine and all external stimulating factors. 3) Avoid sun exposure and ultraviolet radiation, especially in the active period, you can add anti sunlight drugs, such as 3% quinine ointment, compound titanium dioxide ointment, 15% para aminobenzoic acid ointment, etc. other excessive exposure, such as cold, X-ray, can also cause the aggravation of the disease, which can not be ignored.