What reason is uric acid high fall not to fall

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summary

High uric acid is a metabolic disease caused by the increase of uric acid in blood due to the disorder of purine metabolism in human body. The amount of uric acid produced and excreted in the body is equal every day. About one-third of the production comes from food, and the remaining two-thirds is self synthesis in the body. The excretion route of high uric acid is from intestine and kidney; the amount is one third and two thirds respectively. Due to the imbalance of the production and excretion of uric acid in the body, the blood uric acid is increased. The following describes the causes and treatment of high uric acid.

What reason is uric acid high fall not to fall

Reason 1: the cause of high uric acid. Due to the metabolic disorder of purine substances in the body, the synthesis of uric acid increases; exogenous purine intake is too much, and more is obtained from food; endogenous purine production is too much, and enzyme abnormality leads to excessive purine synthesis; purine metabolism increases, such as rhabdomyolysis, polycythemia, etc.

The second reason is the symptom of high uric acid. High uric acid has different manifestations in different stages. Asymptomatic hyperuricemia, blood uric acid concentration increased by blood sampling, but no arthritis, hyperuricemia stone or kidney stone and other symptoms; acute hyperuricemia arthritis can occur in all seasons, the supersaturated uric acid forms needle like crystal deposition in the synovial fluid.

The third reason is the treatment of high uric acid. Prescription drugs for excreting uric acid, such as probenecid, sulpirone and benbromarone, can prevent renal tubular reabsorption of uric acid and increase the excretion of uric acid; allopurinol is the only drug that can reduce the production of uric acid and reduce the level of uric acid in human body; sodium bicarbonate is the drug that alkalizes urine.

matters needing attention

Prevention of high uric acid. Overweight or obesity is a related risk factor of hyperuricemia. Avoiding obesity is an important link to prevent hyperuricemia and gout. We should supplement enough water and salt to avoid spicy.