Myasthenia gravis and seasonal changes

summary

I am a patient with myasthenia gravis. Three years ago, I suddenly found that my eyelids were drooping all the time. Later, I developed into two eyes. After medication, the symptoms improved obviously. I'm so happy. Now let me talk about myasthenia gravis and seasonal changes.

Myasthenia gravis and seasonal changes

Treatment 1: oral or nasal administration, through mucosal induction of immune tolerance, can specifically reduce the antigen of local or systemic immune response. In order to prevent the occurrence of experimental autoimmune myasthenia gravis and inhibit the cellular and humoral immunity against acetylcholine receptor or its peptide, some scholars have given the eel or newborn mice acetylcholine receptor and its subunit A by oral or nasal mucosa before sensitization with acetylcholine receptor. In addition, intranasal administration can avoid the damage of gastric acid and pepsin to the antigen, which requires less antigen dose. A large number of experiments have confirmed that mucosal tolerance alone can only prevent the occurrence of experimental autoimmune myasthenia gravis, and can not effectively block the progress of experimental autoimmune myasthenia gravis.

Treatment 2: immune tolerance induced by dendritic cells, the use of immature dendritic cells, blocking or reducing the immune activation function of dendritic cells, can prevent autoimmune response. The dendritic cells of healthy rats were incubated with transforming growth factor - β 1 and transforming growth factor - γ in vitro, and then injected subcutaneously on the fifth day of experimental autoimmune myasthenia gravis. The results showed that immune tolerance was successfully induced, and the clinical symptoms of experimental autoimmune myasthenia gravis were significantly alleviated. The dendritic cells induced in vitro were the main cause of experimental autoimmune myasthenia gravis Treatment has brought new hope, but its mechanism of action in the treatment of myasthenia gravis is not clear. Moreover, dendritic cells in this state can only prevent the occurrence of experimental autoimmune myasthenia gravis, but can not effectively prevent the progress of the disease.

Treatment 3: Cyclosporin A, which is mainly used for anti rejection of liver, kidney and heart transplantation, can be used with adrenocortical hormone, and can also be used for the treatment of some immune diseases. Adverse reactions: elevated serum creatinine, hypertension, epidemic symptoms, etc.

matters needing attention

For such a disease: dietary guidance, due to the different physical conditions of each patient, each patient's favorite taste is not the same, must be combined with the disease, appropriate care for eating habits, good dietary guidance, when discharged to patients with myasthenia diet guidance prescription, so that patients can consciously cooperate with dietary treatment.