What reason can cause platelet low

summary

Low platelet count is lower than the normal number of platelets in the blood. Platelets are the cellular components of the blood, along with one of the white and red blood cells. Platelets play an important role in coagulation and hemostasis. Platelets in the bone marrow are similar to other cells in the blood. Platelets are megakaryocytes, which are found in a large number of bone marrow cells of origin. Fragments of these megakaryocytes are released into platelets in the blood. The circulating platelets make up about two of the third platelets released from the bone marrow. The other third usually stores (sequesters) the spleen.

What reason can cause platelet low

First, reducing platelet production is usually associated with bone marrow problems. In some of these conditions, the production of red blood cells and white blood cells may also be affected. Affect the bone marrow, such as viral infections: parvovirus, rubella, mumps, chickenpox, hepatitis C, aplastic anemia when the bone marrow can not produce any blood cells.

Second: a platelet count of less than 15 is called thrombocytopenia. A platelet count greater than 400000 is called thrombocytosis. The sequence in which platelets initiate reactions that eventually lead to the formation of blood clots. They circulate in the blood vessels and become activated by whether there is bleeding or damage to the body.

Third: certain chemicals are released from injured blood vessels or signaling platelets are activated and added to other parts of the system to trigger other structures of coagulation. After activation, platelets become sticky and adhere to each other and the injured part of the vascular wall to slow down and block the damaged blood vessels or tissues (hemostasis).

matters needing attention

This can be caused by certain viral infections (parvovirus or HIV), drugs (gold, chloramphenicol, phenytoin, valproate), or radiation, or very little, or it can be congenital (Fanconi anemia).