What is the symptom of hypercalcemia?
summary
Hypercalcemia refers to the abnormal increase of serum ionic calcium concentration. Because the determination is usually total calcium, rather than ionic calcium, we must pay attention to the factors affecting ionic calcium. Serum albumin concentration is the most important factor in clinic, because albumin is the main calcium binding protein in blood circulation. What is the symptom of hypercalcemia? Let's talk about it
What is the symptom of hypercalcemia?
The light ones are weak, tired and indifferent; Severe patients have headache, muscle weakness, weakened tendon reflex, depression, irritability, gait instability, language disorders, hearing, vision and orientation disorders or loss, numbness, behavioral abnormalities and other mental and neurological symptoms.
May cause the blood pressure to rise and each kind of arrhythmia. ECG showed Q-T interval shortening, ST-T changes, atrioventricular block and hypokalemic U wave. If not treated in time, it can cause fatal arrhythmia. Hypercalcemia can lead to increased renal micturition and electrolyte disorder, thickening of bronchial secretions, weakening of ciliary activity of mucosal cells, and poor drainage of bronchial secretions, which can easily lead to pulmonary infection, dyspnea, and even respiratory failure.
Anorexia, nausea, vomiting, abdominal pain, constipation, severe paralytic intestinal obstruction. Calcium can stimulate the secretion of gastrin and gastric acid, so patients with hypercalcemia are prone to peptic ulcer. The ectopic deposition of calcium in pancreatic duct and the stimulation of pancreatic enzyme secretion by calcium can lead to acute pancreatitis.
matters needing attention
Glucocorticoid: in addition to hyperparathyroidism, it can be used to treat hypercalcemia caused by other reasons, and can also be used as the differential diagnosis of the cause of hypercalcemia. Oral prednisone 40-80mg / D, or 200-300mg hydrocortisone intravenous drip, lasting for 3-5 days, has slow onset and short maintenance time, so it is often combined with other calcitonin drugs.
