What are the causes of hemolysis

summary

Hemolysis may have many people do not understand, or just listen to talk, hemolysis may be caused by many reasons, generally occurs in infants more, let's talk about the causes of hemolysis.

What are the causes of hemolysis

First: hemolysis: red blood cell rupture, hemoglobin escape, called red blood cell lysis, referred to as hemolysis. It can be caused by a variety of physical and chemical factors and toxins. In vitro, such as hypotonic solution, mechanical strong oscillation, sudden low temperature freezing (- 20 ℃ ～ - 25 ℃) or sudden thawing, excessive acid or alkali, alcohol, ether, soap alkali, choline salt can cause hemolysis. The isotonic solution of human plasma is 0.9% NaCl solution. In the solution of less than 0.45% NaCl, the red blood cells are ruptured due to the expansion of red blood cells due to the infiltration of water, and the hemoglobin is released.

Second: the input of abnormal blood: that is, blood donors and patients Ab0 blood group does not match the hemolysis caused. Generally, the reaction is rapid, the symptoms occur quickly, and the consequences are more serious. Transfusion of deteriorated blood: before blood transfusion, the red blood cells have been damaged and dissolved. For example, the blood is stored too long, the temperature is too high or too low, the blood is severely shaken, and the blood is polluted. In addition, the addition of hypertonic or hypotonic solution to the blood, the collection and sorting of medical education network, and the addition of drugs that affect pH can cause a large number of destruction of red blood cells in the blood.

Third: hemolytic disease of the newborn refers to a hemolytic disease caused by the blood group incompatibility between the mother and the child. ABO blood group incompatibility is the most common, Rh blood group incompatibility is rare, and other blood group incompatibility can be seen occasionally. The blood groups of hemolytic patients are a, B, AB and o. Type A has a antigen on red blood cells, type B has b antigen, type AB has a and B antigens, and type O has no antigen. Blood type is inherited and determined by the genes of mother and father.

matters needing attention

Hemolysis may occur in the baby when more serious, so to timely treatment, otherwise it may cause other diseases, the baby's body will have a great impact.