What disease is pemphigus

summary

Pemphigus is a serious skin disease, and it is easy to relapse. It is related to its own immunity, and it needs to be treated actively. Now let's see what is pemphigus.

What disease is pemphigus

First of all: pemphigus is a chronic, recurrent, severe intraepidermal acantholysis bullous skin disease. There are antibodies against cadherin, a CA [sup] 2 + [/ sup] dependent intercellular adhesion molecule, in the patients. Therefore, there are relaxant blisters on the normal skin or mucosa, and Nissl sign is positive.

Secondly, the etiology of the disease has not been completely clear, now it is considered to be an autoimmune disease. The main antigen of pemphigus is desmosomes, and the main antibody is IgG. There are four kinds of IgG subtypes, and a few are IgA. The antibody binds to the epidermal cells, leading to the release of the prickles. The cDNA sequence of pemphigus antigen has obvious homology with cadherin, so pemphigus antibody also damages the adhesion function between epidermal cells, leading to the release of prickles.

Finally, the age of onset is quite different. The average age of onset is 50~60 years. Incidence rate of male and female is similar. In China, pemphigus is traditionally divided into four types: common type, proliferative type, deciduous type and erythema type.

matters needing attention

Pay attention to the protection of the wound, do a good job of cleaning and drying. In terms of diet, we should strengthen nutrition and enhance resistance. The usual diet should strengthen nutrition, add more protein, eat more fresh fruits and vegetables, contribute to the recovery of the disease.