What reason is infant jaundice?
summary
When the baby is still a fetus, it relies on the placenta to supply blood and oxygen. Without the mother, the baby begins to breathe with its own lungs to get oxygen. The hypoxic environment in the body has changed, and it no longer needs so many red blood cells. At this time, bilirubin is produced and may be excessive. The excess bilirubin cannot be discharged from the body without a mature enzyme system. It flows with the blood to all parts of the baby's body and reacts to the external signs, that is, the baby's skin and sclera turn yellow. This phenomenon is called neonatal jaundice. What reason is infant jaundice? Let's study and discuss with you.
What reason is infant jaundice?
1. Bilirubin production more (1) red blood cell destruction More: fetal baby in the mother's uterus in hypoxia environment, red blood cells compensatory increase, but short life, increased blood oxygen content after birth, excessive red blood cells were rapidly destroyed( 2) The content of heme oxygenase is high: it is high within 7 days after birth and has great potential to produce bilirubin.
2. Immature liver function (1) the ability of liver to absorb bilirubin is poor: the content of Y and Z protein in liver cells is insufficient, which makes the liver absorb bilirubin insufficiently( 2) The function of liver conjugated bilirubin is poor: the content of glucuronosyltransferase in liver is low and the activity is insufficient, resulting in the poor function of conjugated bilirubin( 3) Liver excretion function of bilirubin is poor: excretion function of conjugated bilirubin is poor, easy to cause cholestasis.
3. Characteristics of intestinal hepatic circulation: the normal intestinal flora has not been established at birth, and bilirubin entering the intestine cannot be converted into urobilinogen.
matters needing attention
1. Pay attention to observe the systemic symptoms of infants with fetal jaundice, such as mental depression, drowsiness, sucking difficulty, restlessness, direct vision, limb rigidity or convulsion, so as to find out and deal with the severe cases as soon as possible. 2. Closely observe the changes of heart rate, heart sound, anemia degree and liver size, and early prevent and treat heart failure. 3. Pay attention to protect the baby's skin, umbilicus and buttocks, keep clean and prevent damage and infection.