How long is the rejection period of bone marrow transplantation for aplastic anemia

Update Date: 2023-12-09 Source: Network

summary

Aplastic anemia is hereditary. This disease existed in our family. Later, I solved it through bone marrow transplantation. At that time, there was no rejection stage, and the prognosis was quite good. Let's see how long the rejection period of aplastic anemia bone marrow transplantation is.

How long is the rejection period of bone marrow transplantation for aplastic anemia

First of all: the time of rejection after bone marrow transplantation varies from person to person, the shortest time is within 1-2 weeks, the acute time is within 100 days, beyond this time is called chronic rejection.

Secondly, transplantation rejection is the main complication of allogeneic bone marrow transplantation for aplastic anemia, and it is also the main cause of death. It is related to the pathogenesis of aplastic anemia. The failure rate of allogeneic bone marrow transplantation without proper preparation is very high, and the rejection rate is 10%. It is suggested that aplastic anemia patients are very sensitive to autoimmune reaction.

Finally: with the improvement of the transplantation protocol, the incidence of GVHD decreased, but until recently, the data still showed that the incidence of GVHD was higher and the degree was more serious in older patients.

matters needing attention

In the skilled transplantation center, because of the short preparation time and less complications of the relative donors, especially for the young patients with severe hemocytopenia, the success rate of the operation can be greatly improved by using the bone marrow matching of the relatives.