What coagulation factor deficiency can vitamin K cause?

summary

Vitamin K deficiency, also known as acquired thrombocytopenia, is a kind of bleeding that can be corrected by vitamin K due to vitamin K deficiency. It is characterized by underlying diseases, bleeding tendency and deficiency or decrease of vitamin K-dependent coagulation factors. What coagulation factor deficiency can vitamin K cause? Let's talk about it

What coagulation factor deficiency can vitamin K cause?

Skin, mucosal bleeding, such as skin purpura, ecchymosis, epistaxis, gingival bleeding. Visceral hemorrhage such as hematemesis, black manure, hematuria and menorrhagia, severe cases can cause intracranial hemorrhage. Bleeding after trauma or surgery.

Neonatal haemorrhage is more common in 2-3 days after birth, often manifested as umbilical cord hemorrhage, gastrointestinal bleeding, etc. The bleeding of this disease is generally mild, and rarely occurs in muscles, joints and other deep tissues.

In severe hepatitis, decompensated cirrhosis and advanced liver cancer, due to the impairment of liver function and the disturbance of vitamin K uptake, absorption, metabolism and utilization, the liver can not synthesize normal amount of vitamin K-dependent coagulation factor.

matters needing attention

It is recommended to use vitamin K1 0.5 ~ 1mg routinely for newborns to prevent hypothrombin and reduce the incidence of intracranial hemorrhage caused by birth trauma. It can also be used prophylactically when considering surgical operation. Either use vitamin K1 at a preventive dose (2 ~ 5mg / D, oral) to the mother one week before the due date of delivery, or give vitamin K1 solution (2 ~ 5mg / D, oral) 6 ~ 24 hours before delivery, Intramuscular injection)