Causes of vitiligo

summary

The tour organized by our unit hospital is quite affordable, but as soon as he came back, he found that something was wrong with him, because there was a white spot on the nose of the neighbor. At first, he didn't notice it, but now it's getting bigger. Let me share the causes of vitiligo.

Causes of vitiligo

First: vitiligo is a common acquired localized or generalized skin depigmentation disease. However, the mechanism is still unclear. It can occur in all parts of the body, common in finger back, wrist, forearm, face, neck and around genitalia. The decrease of copper or ceruloplasmin levels in the blood and skin of patients with vitiligo leads to the decrease of tyrosinase activity, which affects the metabolism of melanin.

Second: female vulva can also occur, young women in the majority. Vitiligo can appear in twins and families, indicating that heredity plays an important role in the pathogenesis of vitiligo. Studies have shown that vitiligo has incomplete penetrance and multiple pathogenic loci. Vitiligo can be combined with autoimmune diseases, such as thyroid disease, diabetes, chronic adrenal insufficiency, pernicious anemia, rheumatoid arthritis, malignant melanoma and so on.

Third: mental factors are closely related to the onset of vitiligo. Most patients have mental trauma, excessive tension, depression or depression at the onset or skin lesion development stage. The degeneration of nerve endings in leukoplakia also supports the neurochemical theory. Antibodies and T lymphocytes can be produced in patients with vitiligo, indicating that the immune response may lead to the destruction of melanocytes.

matters needing attention

Because there are many causes of vitiligo, the treatment method is not the same, and the medication can not be the same, so drug treatment, if you want to achieve curative effect, must be combined with medication, so as to play the purpose of etiological treatment for medication.