What is the best treatment for membranous nephropathy

summary

Dad recently went to the toilet a lot more than before, and the amount of urine is not much, sometimes with some blood, the doctor said this is membranous nephropathy, I am very worried about his condition, so today I will introduce the best treatment of membranous nephropathy.

What is the best treatment for membranous nephropathy

First, non immunotherapy. 5 g / day, In young patients with normal or mild decrease of plasma albumin and normal renal function, the blood pressure should be controlled below 125 / 70mmhg. The first choice of drugs is angiotensin-converting enzyme inhibitor (ACEI) or angiotensin II receptor antagonist (ARB). Anticoagulant therapy can prevent the high incidence of venous thrombosis in patients with membranous nephropathy. The patients with high risk factors (urinary protein > 8g / day, plasma autoprotein < 20g / L, diuretics or long-term bed rest, etc.) should take active anticoagulant therapy.

Second: low molecular weight heparin injection is the first choice of drugs. If patients have long-term hypoproteinemia, oral warfarin anticoagulant therapy can be considered, but coagulation function should be closely monitored. The protein intake should be limited to 0.8g / (kg · d) in the diet of patients with low protein diet and large amount of albuminuria, and sufficient calories should be given at the same time. The total calories should be 146.54kj (35kcal) / (kg · d).

Third: immunotherapy, immunosuppressive therapy depends on the degree of proteinuria, duration and renal function. It is generally believed that high-risk patients with proteinuria > 3.5g/day and renal dysfunction or proteinuria > 8g / day should be given immunotherapy. It is generally believed that glucocorticoid alone (hereinafter referred to as glucocorticoid) is ineffective, and hormone plus cyclophosphamide (CTX) or cyclosporine A (CSA) treatment can make some patients achieve clinical remission.

matters needing attention

In fact, there are many ways to treat membranous nephropathy. We can choose the best way to treat it by cooperating with doctors. We must not ignore the condition and take medicine indiscriminately. In fact, it is not good.