Hormone therapy for polycystic ovary syndrome

summary

In today's life, female friends are troubled by many diseases, which bring serious harm to their health. The emergence of polycystic ovary disease is a painful blow to them. We must actively treat the occurrence of this disease. Now I'd like to introduce hormone therapy for polycystic ovary syndrome.

Hormone therapy for polycystic ovary syndrome

Drug 1: spironolactone is an aldosterone analogue, the effectiveness of enzyme inhibition is similar to that of cyproterone acetate, and the therapeutic effect of the two drugs is similar. Spironolactone has anti androgen effect. The mechanism of spironolactone in the treatment of hyperandrogenemia is that it competitively binds to androgen receptor, competitively binds to dihydrotestosterone receptor in peripheral tissue, and inhibits 17 α hydroxylase. The treatment dose is 50-400mg / day.

Drug 2: fluorinated amide is a kind of sterol complex, which has strong effect and high specificity non steroidal anti androgen. It has no intrinsic hormone or anti gonadotropin effect, and can not reduce steroid synthesis, but inhibits androgen effect through receptor binding. Compared with cyproterone acetate, the level of serum androgen (including total testosterone and free testosterone) increased after treatment. However, due to the antagonism of androgen target organ effect, the clinical manifestations did not worsen despite the increase of serum androgen level. The treatment dose is 250 mg / day. In addition, whether it can cause fetal malformation is still uncertain, so contraception should be used during medication.

Drug 3: clomiphene combined with dexamethasone, human menopausal gonadotropin (HMG) combined with chorionic gonadotropin, gonadotropin releasing hormone agonist combined with human menopausal gonadotropin. The purpose of drug therapy is to induce ovulation, reduce androgen and reconstruct menstrual cycle.

matters needing attention

The diet should be light, rich in adequate nutrition, correct partial diet and abnormal eating habits, and should not eat irritating and seafood. The suitable foods for patients are: milk, spinach, yam, cabbage, rape, mushroom, lean meat, egg, crucian carp, apple, pear, jujube, peanut, etc.