What disease is infantile yaws disease?

summary

Yaws, Pian, franboesia is a non sexually transmitted infectious disease caused by Treponema pertenue. Almost all the patients are children. The main clinical manifestations are painful skin papules, ulcers, scabs and some systemic symptoms. In the late stage, there were destructive changes of bone. What is infantile yaws disease? Let's talk about it now.

What disease is infantile yaws disease?

The source of infection is the patient. In some areas of Africa where human yaws and endemic syphilis are prevalent, there are some non-human primates with antibodies to yastreponema. When the damaged skin contacts the exudate of active Yashi lesion, it can be infected. Insect bites, abrasions, or injuries can promote the natural infection of yastrepone from infected contacts, most likely through fingers directly or indirectly contaminated with early yastrepone damage. Most of the new cases occurred in rainy season, and most of the primary infections occurred before puberty. Shortly after the initial infection, the pathogen can invade the bloodstream, and later cause damage to bone, lymph nodes, and distant skin.

The clinical manifestation of yaws is characterized by one or more skin lesions at first, followed by recurrence, non-destructive secondary damage of skin and bone, and destructive changes of skin, bone and joint in the late stage.

The pathogen of the disease was experimentally inoculated into susceptible human volunteers and the incubation period was confirmed to be 3-4 weeks. At first, a single papule appeared on the skin where spirochete invaded, which gradually expanded into a nodule and became papilloma like. Its surface showed erosion like changes, covered with a thin yellow scab, which was composed of serous exudates containing yastrepone. The diameter of the lesion can reach 3-4cm, with itching or pain. It is called Yashi tumor (raspberry like) or mother tumor. It is more common in the exposed parts of the face and limbs, especially in the lower limbs. The same small lesions appeared around the parent tumor. Local lymph node enlargement. The initial damage usually healed within 3-6 months. Before or after the healing of the primary lesion, secondary skin lesions can be caused by spirochemiasis or autologous inoculation, sometimes accompanied by fever, general soreness and other symptoms. The skin rashes are various, including desquamation macula, papule or bean nodules, covered with thin gray scab, sparsely distributed in the whole body, mainly in the trunk and limbs; It can also develop into bayberry like nodules, covered with dark yellow or brown thick scab. After removing the scab, the surface looks like bayberry like, with a little exudation and bleeding, and tenderness. It is mainly distributed on the outside of the head and limbs. When it occurs in the sole, it can cause crab like gait, so it is called "crab like Yasi". The secondary lesions can disappear after several weeks or months, leaving no trace or pigmentation.

matters needing attention

Children are relatively susceptible to yaws. Lack of clothing, poor sanitation and frequent skin damage are likely to contribute to the occurrence of yaws. Direct contact with the lesion site is the main mode of transmission of the disease, but it may also be transmitted indirectly through insects.