Plexiform neurofibroma symptoms?

summary

There is a colleague who got plexiform neurofibroma. Now he is in hospital. I feel that the disease is so close to us. What are the symptoms of plexiform neurofibroma? So as to be alert.

Plexiform neurofibroma symptoms?

In almost all cases, milk coffee spots were found on the skin at birth, with different shapes and sizes, irregular edges and no protruding skin surface, and most of them occurred on the non exposed parts of the trunk; More than 6 skin milk coffee spots (> 5mm) before puberty (more than 15mm after puberty) have high diagnostic value, and systemic and axillary freckles are also one of the characteristics.

Dermatofibroma and fibrochondroma occur in childhood, mainly in the trunk and face skin, but also in the extremities. Most of them are pink in color, and the number is variable. They can be several thousand in size and vary in size. Most of them are the size of sesame, mung bean to orange, and are soft in texture; Soft tumor is fixed or pedicled, soft and elastic to touch;

The neurofibroma of superficial epidermal nerve is like a bead like nodule, which can move and cause pain, tenderness, radiation pain or paresthesia; Plexiform neurofibroma is a diffuse neurofibroma of the nerve trunk and its branches, often accompanied by a large number of hyperplasia of skin and subcutaneous tissue, causing diffuse hypertrophy of the region or limbs, known as neurofibromatous elephantiasis.

matters needing attention

Fibrochondroma or plexiform neurofibroma can be seen in the upper eyelid. The mass and exophthalmos pulsation can be palpated in the orbit. Small orange round nodules of iris miliary can be seen by slit light. It is hamartoma, also known as Lisch nodules, which can increase with age. It's unique to NFI. Gray white tumor and optic papilla were seen in fundus; Optic gliomas can cause exophthalmos and loss of vision.