How long does uterine cancer chemotherapy need?
summary
Cervical cancer, also known as cervical invasive cancer, is the most common gynecological malignant tumor. It is often caused by fire, the high incidence age is 35-39 years old and 60-64 years old, but the incidence of cervical cancer has a younger trend recently, which is mainly related to premature sex life, excessive frequency, multiple sexual partners and virus infection, especially the relationship between HPV and cervical cancer has been confirmed. So how long does it take for a patient to have chemotherapy for uterine cancer?, Today I'd like to share this with you.
How long does uterine cancer chemotherapy need?
First: application of PVB regimen: first line chemotherapy for advanced cervical cancer. One day before chemotherapy, hydration: (1) 5% GS 500ml vitamin C 2G once a day, intravenous drip; (2) 0.9% NaCl 1000ml 10% KCI 10ml once a day, intravenous drip; (3) Ringer's solution 500ml once a day, intravenous drip; (4) furosemide (furosemide) 20mg once a day, intravenous injection
Second: chemotherapy prescription: (1) 0.9% NaCl 100 ml cimetidine 0.4 g once a day, intravenous drip, the first day (2) 0.9% NaCl 100 ml vincristine (VCR) 1.2 mg / m2 once a day, intravenous drip, the first day (3) 0.9% NaCl 100 ml ondansetron 8 mg once a day, intravenous drip, the first to the eighth day (4) 0.9% NaCI 500 ml cisplatin (DDP) 50 mg / m2 once a day, intravenous drip, On the first day (5) furosemide 20 mg once a day, intravenous injection, on the first and second days (6) 0.9% NaCl 500 ml 10% KCl 10 ml once a day, intravenous injection, on the first and second days (7) 5% GS 1000 ml vitamin C 2 g vitamin B6 200 mg 10% KCl 10 ml once a day, intravenous drip, on the first and second days (8) 20% mannitol 250 ml once a day, intravenous drip, on the first and second days (9) 0.9% NaCl 30 ml once a day, intravenous drip for 24 hours, Bleomycin (BLM) 25mg / m2 was repeated every 3 weeks for 3 courses from day 1 to 8.
Application: the first-line chemotherapy for cervical cancer. 2. Prescription (1) 0.9% NaCI 100 ml ondansetron 8 mg once a day, intravenous drip, 1,22 days, after two courses of treatment, once every 5 weeks (2) 0.9% NaCI 100 ml I mitomycin 10 mg / m2 once a day, intravenous drip, 1 day (3) 0.9% NaCl 500 ml once a day, intravenous drip, 1,22 days (4) 0.9% onacl 500 ml cisplatin 50 mg / m2 once a day, intravenous drip, 1,22 days, 22 days (5) furosemide (furosemide) 20 mg once a day, intravenous injection, 1, 22 days, repeated every 6 weeks, a total of 3 courses.
matters needing attention
1. Local tissue necrosis: pain, swelling and local tissue necrosis can be caused if the injection of vincristine and adriamycin is missed subcutaneously. Therefore, special attention should be paid to the route of administration. In case of drug leakage, it should be diluted with 1 / 10 equivalent sodium thiosulfate solution or normal saline by local injection immediately, and cold compress with ice bag instead of hot compress. 2. Embolic phlebitis: phlebitis or embolic phlebitis is often caused by intravenous injection. Therefore, we must pay attention to the concentration of intravenous injection, which is usually injected after dilution or flushed into the infusion tube. In addition, we should pay attention to changing the blood vessels of drug delivery frequently, starting from the distal venule in a planned way.