What symptom does gastrinoma have?

summary

Gastrinoma is a kind of gastrointestinal and pancreatic neuroendocrine tumor, characterized by refractory, recurrent or atypical peptic ulcer and high gastric acid secretion, also known as Zhuo AI syndrome. The etiology of gastrinoma is unknown, and it may originate from the pancreas α 1 cell. Because gastrinoma is mostly seen in pancreatic tissue, rarely in other tissues outside the pancreas, and the tumor is small, it is sometimes difficult to accurately locate the tumor. However, in recent years, with the improvement of B-ultrasound, CT or MRI diagnostic technology, it has created a good condition for tumor location. If there is no distant metastasis, the tumor can be cured after resection. Now let's talk about the symptoms of gastrinoma

What symptom does gastrinoma have?

1. Abdominal pain is caused by peptic ulcer, which may have a family history of peptic ulcer. This is due to gastrin strong and continuous stimulation of gastric mucosa, resulting in a large amount of gastric acid and pepsin secretion. Ulcer often presents single, also can many, diameter is general 2 centimeters.

2. Patients with diarrhea may have diarrhea. Some cases of diarrhea can occur when the ulcer, the disease can be the first symptom or the only symptom. A few patients had diarrhea but no ulcer. Diarrhea often presents as massive, watery and fatty diarrhea. 10-30 times a day. Severe cases can produce water and electrolyte disorders, and dehydration, hypokalemia and metabolic acidosis and other symptoms.

3. Some patients with multiple endocrine neoplasia may be complicated with other endocrine tumors. The distribution of endocrine glands involved was parathyroid gland, pancreas, pituitary gland, adrenal gland and thyroid gland. There were corresponding clinical manifestations related to endocrine gland hyperfunction.

matters needing attention

In fact, stomach disease can be prevented. This is to pay attention to diet hygiene in daily life. However, people suffering from stomach disease should also pay attention to the use of various kinds of drugs. They should strictly follow the doctor's advice and use them with caution, so as to avoid causing damage to the stomach.