What is the cause of eosinophilic granuloma of bone?

summary

Few people have heard of eosinophilic granuloma of bone. In fact, the disease is harmful to people's health. It can cause asthma, joint pain, fever and other symptoms. It needs to be treated to prevent future problems. This is because the disease of eosinophilic recurrent granulomatous dermatitis produces some erythema on the body, Some people because of animal bites, or drug allergy, what is the cause of bone eosinophilic granuloma? Now let me tell you something.

What is the cause of eosinophilic granuloma of bone?

First, eosinophilic granuloma of bone generally refers to histiocytosis confined to bone, which belongs to a type of histiocytosis. Histocytes and eosinophils accumulated in osteolytic lesions. Osteolytic destruction of the pelvis, jaw, ribs and scapula is the main feature, and reactive sclerosis of the upper edge of the acetabulum destruction area is an important medical sign to evaluate the diagnosis of this disease.

Second: the differential diagnosis obviously needs to be closely combined. Conclusion for clinical consideration, fatigue mainly needs to be considered with osteomyelitis, metastatic tumor, bone tuberculosis, xanthoma, myeloma, etc. the differential diagnosis is generally based on clinical perception and X-ray findings. I don't know if the final diagnosis depends on local biopsy.

Third: because of the location of the disease and ectopic lesions in the skull for limited bone destruction, can be single or multiple, skull inner and outer plates are damaged, sharp edge and bending, scapular lesions for sharp edge, obvious boundaries of bone destruction, vertebral collapse after destruction, so that the vertebral body upper and lower epiphyseal plate combined with healthy search together, intervertebral space without abnormality.

matters needing attention

Treatment of eosinophilic granuloma of bone, curettage and bone grafting or radiotherapy are effective treatment methods, pathological fracture according to the principle of fracture management. Curettage and bone grafting are feasible for single lesion, and resection is feasible for rib lesion.