How is fixed sex drug eruption to return a responsibility?

summary

Most drugs have the possibility of causing drug eruption, you can eat some light things, including herbal medicine, but the stronger antigenicity caused the most. Most of them are sulfonamides, butazone, indomethacin, phenytoin sodium, barbital, etc. In addition, for patients with congenital allergic diseases and diseases of important organs, the risk of drug eruption is relatively high. So the following is a specific introduction to fixed drug eruption is how to return a responsibility? I hope this problem can help some people.

How is fixed sex drug eruption to return a responsibility?

First, the shape of fixed drug eruption is special and easy to identify. It is characterized by local pruritus, followed by round or oval erythema, the color is bright red or purple red, with edema, the more frequent the attack, the deeper the pigment, the more visible the remaining pigmentation. The obvious difference between this rash and other rashes is that it often occurs at the same site after taking the same drug each time. Generally speaking, fixed drug eruption occurs in external genitalia, lips and the back of hands. This drug eruption has a certain incubation period, which usually occurs within 4-20 days after the first medication. If the body is in a sensitized state after repeated medication, it will occur within 24 hours, while the sensitive person can occur within a few minutes or hours.

Second, according to relevant research statistics, the drugs causing fixed drug eruption are mainly sulfonamides, such as long-acting sulfonamides, sulfaguanidine, SMZ, etc; Secondly, antipyretic analgesics, such as analgin, aspirin, quick acting cold capsules, etc; There are sleeping sedatives, such as lumina, speed can sleep, and barbiturates for more common. Some compound drugs contain the above three drug components, and this type of drug eruption can also occur. For example, some compound cold drugs often contain aspirin, which can induce this disease.

Third: the clinical manifestations of acute onset, skin lesions for isolated or a number of clear boundary round or oval edema erythema, generally asymmetric, 1-4cm in diameter, severe erythema can appear bullae. There is itching and no general symptoms. Lesions can occur in any part of the skin. In the lip, mouth, glans, anus and other skin mucosa junction, often prone to erosion or secondary infection and pain, at this time, patients often come to the emergency department. The skin lesions lasted for 1 week, leaving gray black pigmentation spots, lasting for a long time. When the drug is taken again, it itches in the original place within a few minutes or hours, and then the same damage appears and expands to the surrounding area, resulting in the central pigment deepening and edge flushing damage. When recurrence occurs, new lesions may appear in other parts.

matters needing attention

1. According to the general routine nursing of dermatology department. 2. Give high Dan White, high vitamin liquid or semi liquid diet. 3. Strengthen the care of facial features and mucous membrane to prevent the occurrence of complications. 4. There should be a significant mark for sensitizing drugs to prevent the recurrence of allergy. 5. Keep the bedding and clothes clean, dry and flat. 6. Strictly aseptic operation, puncturing and draining the bullous lesions in the low position or sucking out the blister fluid with an empty needle, paying attention to the protection of the wound surface, and removing the infected epidermis.