How is gastrinoma to return a responsibility?

summary

Gastrinoma is caused by gastric antrum G cell proliferation or gastrin secreting tumor. It is characterized by multiple and refractory peptic ulcer of upper digestive tract caused by hypergastrinemia and large amount of gastric acid secretion.

How is gastrinoma to return a responsibility?

First, because gastrinoma is more common in pancreatic tissue than in other tissues outside the pancreas, and the tumor is small, it is sometimes difficult to accurately locate the tumor, but in recent years, with the improvement of B-ultrasound, CT or MRI diagnostic technology, it has created a good condition for tumor location. If there is no distant metastasis, the tumor can be cured after resection.

Second: due to the nutritional function of gastrin, the gastric mucosa is hypertrophic, and the capacity of parietal cells can reach 3-6 times of that of normal people, resulting in excessive secretion of gastric acid and gastric juice.

Third: multiple endocrine tumor type I is an autosomal gene abnormality with high penetrance, which is located on chromosome 11. It is possible that all patients with multiple endocrine tumor type I involve three organs (parathyroid gland, islet and pituitary gland), but they do not always have clinical manifestations of excessive hormone. Patients with multiple endocrine tumors of type I with hyperparathyroidism usually develop gastrinoma.

matters needing attention

Don't eat food that is already cold. If it's cold, heat it up. And don't drink cold water. Try to drink cold boiled water. Don't eat greasy food. People with high stomach acid should avoid acidic and fatty food.