Why can you get gastritis

summary

What causes chronic gastritis? Chronic gastritis does not heal for a long time. Pain is difficult to disappear, often caused by blood stasis. In traditional Chinese medicine, it is said that the patient's collaterals have been for a long time. Why do you have gastritis.

Why can you get gastritis

Reason 1: long term use of irritating food and drugs, such as strong tea, liquor, spicy or salicylate drugs, or insufficient chewing when eating, repeated damage to gastric mucosa caused by rough food, or excessive smoking. Nicotinic acid directly acts on gastric mucosa.

Reason 2: duodenal juice reflux study found that chronic gastritis patients with pyloric sphincter dysfunction, often cause bile reflux, may be an important pathogenic factor. Phospholipids in pancreatic juice, together with bile and pancreatic digestive enzymes, can dissolve mucus, destroy gastric mucosal barrier, and promote the anti diffusion of H + and pepsin into the mucosa, causing further damage. The chronic gastritis is mainly in the antrum. Gastritis caused by bile reflux is very common in patients with gastrojejunostomy. Peptic ulcer patients are almost accompanied by chronic gastric sinusitis, which may be related to the dysfunction of pyloric sphincter. Nicotine in tobacco can relax pyloric sphincter, so long-term smokers can promote bile reflux and cause gastric sinusitis.

The third reason: the change of immune factors and immune function has been paid attention to in the pathogenesis of chronic gastritis. Parietal cell antibodies can be found in the blood, gastric juice or atrophic mucosa of patients with atrophic gastritis, especially in patients with gastric body gastritis; internal factor antibodies can be found in the blood of patients with gastric atrophy and pernicious anemia, which indicates that autoimmune reaction may be the cause of some chronic gastritis. However, whether there are immune factors involved in the pathogenesis of gastritis remains to be determined.

matters needing attention

There were diffuse lymphocytic infiltration in gastric mucosa of atrophic gastritis, and abnormal lymphoblastic transformation test and leukocyte migration inhibition test in vitro, suggesting that cellular immune response may be of great significance in the occurrence of atrophic gastritis. Some autoimmune diseases, such as chronic thyroiditis, hypothyroidism or hyperthyroidism, insulin-dependent diabetes, chronic adrenocortical hypofunction, can be accompanied by chronic gastritis, suggesting that the disease may be related to immune response.