How is migratory nodular panniculitis caused?

summary

Migratory nodular panniculitis is a special clinical syndrome characterized by the appearance of one or more red skin nodules in the front of bilateral or unilateral legs, which rapidly expands to the surrounding areas and forms hard plaques, which can subside spontaneously after a few months. How is migratory nodular panniculitis caused? Next, I'd like to share my views with you.

How is migratory nodular panniculitis caused?

It's not clear. It may be related to bacterial and viral infection, and often has a history of acute upper respiratory tract infection, tonsillitis or acute laryngitis 1-20 days before the appearance of skin lesions,

In some cases, skin lesions occurred after mild trauma, but no bacteria and virus were found in the culture of skin lesions. The pathogenesis is not clear. It was speculated that it was related to bacterial and viral infection, but no bacterial and viral infection was found in skin lesion culture.

Skin biopsy showed normal epidermis and mild inflammation in the subdermis, which began to spread from the lipid membrane. The pathological changes were limited to the fat septum between the fat lobules, which could be widened. There were a large number of histiocytes and epithelioid multinucleated giant cells in the lobules,

matters needing attention

1. Remove the infection focus, pay attention to health, strengthen physical exercise, improve the autoimmune function. 2. Regular life, work and rest, happy mood, avoid strong mental stimulation. 3. Strengthen nutrition, fast raw and cold, pay attention to warm supplement. 4. Secondary prevention, early diagnosis and early treatment.