What symptom does gastrinoma have?

summary

Gastrinoma, as we call it, is a kind of tumor with the function of secreting gastrin. It is mainly characterized by excessive secretion of gastric juice and acid, hypergastrinemia, multiple and atypical sites, refractory peptic ulcer or diarrhea and other syndromes. What are the symptoms of gastrinoma we got? I'll share what I know with you

What symptom does gastrinoma have?

The most common clinical manifestation of gastrinoma patients is peptic ulcer. Its symptoms are often similar to those of common peptic ulcer patients, but the symptoms are persistent and progressive, and the response to treatment is poor

The distribution of upper gastrointestinal ulcer in patients with gastrinoma is similar to that of common peptic ulcer. About 75% of patients with gastrinoma have ulcer located in the first segment of duodenum, and gastric ulcer is rare

Prospective studies have shown that the clinical course of gastrinoma patients with lymph node metastasis is different from that of patients with liver metastasis. Patients with only local lymph node metastasis but no liver metastasis were rarely died due to tumor invasion

matters needing attention

A small number of patients with gastrinoma have fatty diarrhea, which can precede peptic ulcer symptoms for 8 years. About 7% of patients with gastrinoma develop diarrhea without ulceration. Diarrhea is mainly caused by a large amount of hydrochloric acid in the upper digestive tract