What is uremia?

summary

Chronic renal failure (CRF) is a clinical syndrome composed of a series of symptoms and metabolic disorders caused by various renal diseases leading to progressive and irreversible decline of renal function until the loss of function. What is uremia? Let's talk about it

What is uremia?

Metabolic acidosis, chronic renal failure, uric acid, metabolic products, such as phosphoric acid, sulfuric acid, etc., are caused by urinary excretion and can cause "uremic acidosis *". In mild chronic acidosis, most patients have less symptoms, but if HCO3 in arterial blood is less than 15 mmol / L, obvious anorexia, vomiting, weakness, deep breathing and so on may appear.

* disturbance of water and sodium metabolism is mainly manifested as retention of water and sodium, or hypoxemia and hyponatremia. When the renal function is not complete, the ability of the kidney to adapt to excessive sodium load or volume gradually decreases. If the patients with uremia don't limit the water properly, it can lead to excessive volume load, common subcutaneous edema (eyelids, lower limbs) or / and body cavity effusion (pleural cavity, abdominal cavity). At this time, it is easy to have high blood pressure, left ventricular dysfunction (chest tightness, decreased activity tolerance and even can't lie flat at night) and brain edema.

When the patient has a lot of urine, and excessive water restriction, or complicated with vomiting, diarrhea and other gastrointestinal symptoms, it is easy to lead to dehydration. In clinical practice, excessive volume load is more common, so uremic patients should pay attention to the appropriate control of water intake (in addition to drinking water, but also including soup, porridge, fruit and other water rich food), in the process of diagnosis and treatment should avoid excessive fluid infusion, in order to prevent the occurrence of heart failure and pulmonary edema.

matters needing attention

The most important measure to prevent kidney disease is to strengthen physical exercise and enhance the body's disease resistance. There are many ways to exercise, such as walking, long-distance running, dancing, mountaineering, rowing, martial arts, qigong, Taijiquan and so on, which are all conducive to strengthening the physique, improving the body's resistance, and preventing the occurrence of immune reaction damage after infection with bacterial virus.