Does metastatic skin calcification need operation?

summary

Metastatic skin calcification is a disease caused by the deposition of insoluble calcium salts (mainly amorphous calcium phosphate or a small amount of calcium carbonate) in the skin or subcutaneous tissue. It can be divided into three types: metastatic calcification, dystrophic calcification and idiopathic calcification.

Does metastatic skin calcification need operation?

Most of them occurred in renal hyperparathyroidism and osteodystrophy. The lesions were hard white papules with linear or symmetrical nodular plaques. White granular material could be squeezed out from the rash and nodules. It is mainly a hard subcutaneous nodule near the large joint. With the increase of nodule, wave motion may appear. Calcification may occur in or around the deep dermis or subcutaneous tissue, leading to occlusion and embolic ulcer of these blood vessels, especially in the lower leg.

Histopathology: subcutaneous tissue is generally large calcium deposits, in the inner dermis is usually granular and small deposits. Infarct necrosis, calcification of the involved vessel wall. When stained with hematoxylin violet, the calcium deposit is dyed into dark blue, which is easy to be diagnosed. The diagnosis can be made according to the clinical manifestations, skin lesions and histopathological features.

This disease mostly occurs in renal hyperparathyroidism and osteodystrophy. The lesions were hard white papules with linear or symmetrical nodular plaques. White granular material could be squeezed out from the rash and nodules. It is mainly a hard subcutaneous nodule near the large joint. With the increase of nodule, wave motion may appear.

matters needing attention

Calcium edetate sodium (EDTA disodium) can be used to treat primary generalized lesions; For those with hypercalcemia, the intake of calcium should be limited; Phosphorus intake should be restricted with high blood phosphorus, while Aluminium Hydroxide Gel should be given to reduce phosphorus absorption. Local single lesion can be removed surgically.