Is allogeneic bone marrow transplantation risky

summary

Many people may not know very well what kind of situation the allogeneic bone marrow transplantation is. In fact, it is a way of bone marrow transplantation. I believe you have heard about it. Let's talk about the risk of allogeneic bone marrow transplantation.

Is allogeneic bone marrow transplantation risky

First, any hematologic malignancies such as leukemia, lymphoma, myeloma, myelodysplastic syndrome, aplastic anemia, thalassemia and other traditional indications of bone marrow transplantation can be all matched bone marrow transplantation. Allogeneic hematopoietic stem cell transplantation is a radical treatment for adult leukemia.

Second, it is considered that HLA matched donor is the first choice of bone marrow. However, the limitation of donor matching is the main obstacle for many leukemia patients to get this radical treatment. The scarcity of siblings makes it less than 10% likely to have matching donors. In the past, donor recipient HLA mismatching led to acute rejection after transplantation.

Third, close monitoring and early treatment of infection complications should be emphasized after allogeneic bone marrow transplantation. The success rate of implantation after transplantation is basically the same as that of traditional transplantation, but the growth rate of implanted cells is slightly slower, but the process of growth retardation is the process of its anti-tumor effect. Therefore, the recurrence rate of diseases after allogeneic bone marrow transplantation is lower.

matters needing attention

In general, there are certain risks in the allogeneic bone marrow transplantation, but the specific situation must be combined with the patient's physical quality and the development of the disease before we can draw some conclusions, so the patient's mentality must be very good, which is helpful for recovery.